When aliquots of urine controls for drugs of abuse testing were supplemented with different amounts of zinc sulfate, false-negative drug test results were observed except for amphetamine Conclusions: Zinc sulfate can invalidate urine drug and alcohol testing but can be detected using the novel spot tests developed However, in contrast to the observations of Venkatratnam and Lents, the amphetamine test was not affected in this investigation Venkatratnam and Lents 13 already demonstrated that zinc sulfate can interfere with methamphetamine, cocaine, and marijuana testing Can Cold Urine Pass A Drug Test Venkatratnam and Lents 13 already demonstrated that zinc sulfate can interfere with methamphetamine, cocaine, and marijuana testing. The change in specific gravity of urine upon the addition of increasing amounts of zinc sulfate was investigated Herein, these claims are investigated using standard drug detection kits and urine samples adulterated with zinc These specimens were also tested by Intect 7 urine test strips to evaluate whether Intect 7 could detect zinc sulfate in urine Urine alcohol level was also determined by using the Vista analyzer with an enzymatic alcohol assay kit obtained from Siemens Diagnostics To our knowledge, negative interference of zinc sulfate in urine alcohol testing has not been reported To our knowledge, negative interference of zinc sulfate in urine alcohol testing has not been reported. Calcium, cobalt, copper, iron, and nickel resulted in the formation of precipitates with the sodium hydroxide spot test; however, the precipitates formed were not soluble in excess sodium hydroxide Aliquots of a negative urine pool were supplemented with increasing amounts of zinc sulfate 0 In both spot tests, appearances of precipitates are different from urinary sediment Urine specimens with a high glucose content or positive for ketone bodies were tested with the spot tests to ensure that they did not produce false-positive results in the presence of high glucose and ketone bodies In addition, aliquots of discarded patient urine specimens that tested positive for cocaine tested as benzoylecgonine , opiates, marijuana, or benzodiazepines were supplemented with zinc sulfate, and drug tests were repeated to determine the effect of zinc sulfate on urine specimens that originally tested positive for abused drugs Reddit Pass A Drug Test In addition, aliquots of discarded patient urine specimens that tested positive for cocaine tested as benzoylecgonine , opiates, marijuana, or benzodiazepines were supplemented with zinc sulfate, and drug tests were repeated to determine the effect of zinc sulfate on urine specimens that originally tested positive for abused drugs. Significant declines in urinary alcohol concentration in the presence of zinc sulfate using the Vista analyzer were observed Table 4 The first spot test is fairly specific for identifying zinc ion in urine because zinc ion has the unique feature of forming a white precipitate of zinc hydroxide in the presence of sodium hydroxide, which is soluble in excess sodium hydroxide Furthermore, 20 negative urine specimens were tested with both spot tests, and no false-positive response was observed Recently, websites have claimed that zinc sulfate can be an effective adulterant to bypass drug testing .

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Fortunately, elevated blood lead levels are rare, occurring in approximately 6

Zinc sulfate also falsely reduced measured urine alcohol level in urine Therefore, the effect of zinc sulfate on testing all these drugs was investigated Our results are consistent with observations by Venkatratnam and Lents Our results are consistent with observations by Venkatratnam and Lents. When aliquots of urine controls for drugs of abuse testing were supplemented with different amounts of zinc sulfate, false-negative drug test results were observed except for amphetamine However, the concentrations produced for these drugs are semiquantitative Twenty drug-free urine specimens and urine containing high amounts of sugar or reducing substances were tested with no false-positive spot test results observed The Adulta-Check 10 urine test strip is not effective in identifying zinc sulfate

Alcohol and drug abuse is a significant public health issue in the United States and many countries worldwide

However, these high concentrations for these interfering substances are unlikely in a clinical situation DOI: People try to beat drug tests by either ingesting a detoxifying agent or adding adulterant in vitro to a urine specimen after collection Recently, websites have claimed that zinc sulfate can be an effective adulterant to bypass drug testing A detoxifying agent results in diluted urine that can be identified by low creatinine in urine To find a suitable method for detecting zinc sulfate in adulterated urine Similar results were observed when increasing concentrations of zinc sulfate were added to aliquots of a drug-free urine pool supplemented with abused drugs or metabolites followed by repeated drugs of abuse testing However, these novel spot tests can effectively identify the presence of zinc sulfate in urine How To Pass A Saliva Drug Test For Morphine Since then, numerous methods have been employed to subvert these drug tests, adulteration of urine samples being the most common In addition, albumin Sigma , creatinine Fisher Scientific, Waltham, MA , urea Fisher Scientific , calcium chloride Fisher Scientific , magnesium sulfate Fisher Scientific , cobalt chloride Sigma , copper sulfate Sigma , ferric chloride Fisher Scientific , nickel sulfate Sigma , and lead nitrate Sigma were also purchased to perform potential interferences of these substances with spot tests for zinc sulfate Only lead was found to produce a false-positive result with the spot tests we developed No positive response was observed, indicating that high glucose or ketone bodies do not interfere with these spot tests Urine samples from acute marijuana smokers were also obtained in order to study the effects of zinc supplements on THC drug testing In response, the Substance Abuse and Mental Health Services Administration SAMHSA put forth many revisions, strict procedural guidelines, and specimen validity testing criteria to manage suspicious and adulterated samples during and after urine collection Also, no suitable method could be established to detect zinc in urine samples The authors further commented that no method is available to detect the presence of zinc sulfate in adulterated urine, including the recently introduced AdultaCheck 10 dipstick for detecting urinary adulterants .

D, Precipitate in the sodium hydroxide spot test becomes soluble with excess sodium hydroxide Therefore, 2 rapid spot tests were developed in this report for detecting the presence of zinc sulfate in urine How To Pass A Thc Drug Test In 5 Days Venkatratnam A, Lents NH The alcohol assay on the Vista analyzer is an enzymatic assay using alcohol dehydrogenase enzyme Herein, these claims are investigated using standard drug detection kits and urine samples adulterated with zinc Drug-free urine samples were fortified with different amounts methamphetamines and benzoylecgonine, to which zinc sulfate was added to study its effect A wide variety of adulterants has been reported to date along with suitable methods of their detection These 2 solutions were used for the 2 spot tests developed for detecting the presence of zinc sulfate in urine Consequently, a job can be denied to an individual submitting an adulterated specimen Urine is the preferred specimen in preemployment drug testing, and urine specimens are screened for the presence of abused drugs using immunoassays approved by the Food and Drug Administration Venkatratnam, A Conclusions: Zinc sulfate can invalidate urine drug and alcohol testing but can be detected using the novel spot tests developed My Boos Told Me Who Didnt Pass A Drug Test Methods: Two rapid spot tests to detect the presence of zinc sulfate in urine were developed Results were thus measured before and after supplementation with zinc sulfate for comparison The specific gravity increased to only 1 However, 9 drugs amphetamine, barbiturates, opiates, benzodiazepines, marijuana metabolite, methadone, benzoylecgonine, phencyclidine, and propoxyphene are routinely analyzed in our institution .

However, 9 drugs amphetamine, barbiturates, opiates, benzodiazepines, marijuana metabolite, methadone, benzoylecgonine, phencyclidine, and propoxyphene are routinely analyzed in our institution

Venkatratnam and Lents 13 studied the effect of zinc sulfate on testing for 3 drugs of abuse Therefore, zinc sulfate is an effective in vitro adulterant if a drug is present modestly over the cutoff concentration Therefore, specimen integrity testing cannot identify the presence of zinc sulfate in urine Marijuana is the most commonly used illicit drug; cocaine abuse continues to be widespread among the general population For example, the specific gravity of a urine specimen was 1

Zinc can be an effective adulterant in urine for some illicit drugs that are commonly screened under routine drug testing